Naython Muir was found injured in Parkside Road at around 10.45pm on October 13.
The 43-year-old was pronounced dead at the scene shortly after.
His next of kin have been informed and a formal identification awaits.
Detective Chief Inspector Brian Howie from the Met’s Specialist Crime Command, who is leading the investigation said: “We are the very early stage of our investigation and my team of experienced detectives are working diligently to find out who is responsible and to establish the full circumstances of Naython’s murder and why he was attacked.
“I am appealing to anyone who was in the area and witnessed this incident, or the events leading up to it, to get in contact.
“I am particularly keen to speak to people who were in the vicinity of Parkside Road, Argyle Road and St Stephen’s Road between 10pm and 11pm – you may have seen or heard something that could assist us.
“I would also ask residents to check CCTV, dash cam and doorbell cameras to see if they have captured anything of interest.
“We have set up a dedicated web portal where material can be uploaded.
“Someone must know why Nathyon, also known as ‘Nayff’, was attacked – his family are devastated and are desperate for answers.
“If you can help, then please get in touch.
“A crime scene remains in place and I thank the community for their patience while this vital work is carried out.
“The Met is committed to tackling violence of all kinds, and my team of experienced detectives are working diligently to find out who is responsible.”
No arrests have been made as police enquires into the circumstances continue.
A post-mortem examination will be scheduled in due course.
A spokesperson for Metropolitan Police said: “Detectives are appealing for witnesses and information following a murder in Hounslow.
“An investigation was launched after police were called at approximately 22:45hrs on Friday, 13 October to reports of a stabbing in Parkside Road, TW3.
“Officers and London Ambulance Service attended but despite their efforts he died at the scene.
“His next of kin have been informed and, while formal identification awaits, he can be named as 43-year-old Naython Muir from Hounslow.
“A post-mortem examination will be scheduled in due course.
“Anyone with information is asked to contact police on 101 or ‘X’ @MetCC and quote CAD8926/13Oct. You can upload material including video footage here .
“If you do not feel comfortable speaking to police, you can provide information anonymously to the independent charity Crimestoppers on 0800 555 111.
“At this stage there has been no arrest, and enquiries continue.”